Poland Vindicated by not using H1N1 vaccine?

Poland Vindicated by not using H1N1 vaccine? - Washington Times

The decision seemed fraught with risk: a government refusing to import swine flu vaccines amid worldwide warnings of a spreading epidemic.

But Poland did just that, becoming the only country worldwide known to reject the vaccines over safety fears and distrust in the drug companies producing them — concerns international health experts reject as unfounded.

Now that the current outbreak appears to have peaked in much of Europe, many Poles say their government has been vindicated: Countries with large stockpiles often saw low public interest in the vaccines and face financial loss from unused doses set to expire. Poland's government didn't spend a cent fighting the epidemic.

All along, the decision by Prime Minister Donald Tusk and Health Minister Ewa Kopacz met with broad support. Even with 145 swine flu deaths in Poland to date, many Poles view the rejection of the vaccines as a laudable gesture of defiance against pharmaceutical companies, sentiment shaped by a strengthening anti-vaccine movement and conspiracy theories about the vaccines circulating on the Internet.

"I had the impression that the information about swine flu was manipulated in order to create a panic," said Barbara Lazniewska, a 38-year-old architect who was among the many Poles to applaud the government's stance.

Poles take pride in having a strong independent streak, and many respect the government for defying the European Union, the World Health Organization and other international groups that urged countries to implement vaccination programs — advice that smacked to some of meddling in internal affairs.

The prime minister described Poland as a country with the rare "courage" to refuse a vaccine that he said has not undergone sufficient testing.

"We are making this decision only in the interest of the Polish patient and the taxpayer," Mr. Tusk insisted in December. "We will not take part because it's not honest and it's not safe for the patient."

The anti-vaccine movement argues that the vaccine is untested or contains risky ingredients, such as the preservative thimerosal. However, there is little difference in the formulation for the swine flu vaccine and that of the regular flu vaccine, which is available in Poland, and all evidence so far suggests it is safe and effective. WHO says more than 150 million people have been vaccinated in more than 40 countries and no unusual or dangerous side effects have been seen.

"The saving grace for Poland is that this swine flu pandemic is so far very mild. It would be a big scandal if this were a virus that would cause many deaths," said Dr. Andrew McMichael, an immunologist and the director of the Weatherall Institute of Molecular Medicine at Oxford University.

H1N1: WHO still looking for their role in Pandemic influenza

Senior World Health Organisation official Keiji Fukuda said Thursday that it was too early to declare the swine flu pandemic over, as it continues at "high levels" in parts of Europe and central Asia.

Although the A(H1N1) flu virus is peaking and even declining in parts of the northern hemisphere, and is hardly present in the south, Fukuda said there was an unproven possibility that there could be another wave later in the winter.

"It really probably remains too early to call the pandemic over," Fukuda said in a weekly telephone news conference.

Fukuda, Special Adviser to the WHO Director-General on Pandemic Influenza, said flu "activity continues at quite high levels in several different countries" notably the Czech Republic, France, Kazakhstan, Kyrgyzstan, Russia and Switzerland.

Fukuda also noted that the signs of a peak and a decline in the caseload in North America and parts of Europe had occurred "extraordinarily early for influenza," with several months of the winter left.

As a result, the WHO could not rule out the possibility of another wave of illness in late winter or early spring.

"We simply are unable to answer this question right now. We continue to assess, right now we cannot predict whether we will see another upsurge in activity in the earlier parts of 2010," Fukuda said.

Thailand records first case of Human- to-Pigs Swine Flu Transmission

Thailand confirmed Thursday its first case of a pig infected with swine flu spread from humans, senior officials said.

Agriculture minister Thira Wongsamut said that one of 80 pigs in a sample group tested for the virus at Kasertsart University farm in the central province of Sara Buri had contracted A(H1N1) influenza.

"It was only in one sample that we found the A(H1N1)," Thira said.

The ministry has quarantined a five kilometre-radius around the farm, where university research is carried out, as a precautionary measure, he said, adding that new health checks would be conducted at the farm every three days.

The ministry's permanent secretary Yukol Limlamthong said that none of the 132 workers at the university farm had contracted swine flu. He could not confirm if a research student had brought the virus in.

"We can not prove that, but the test results show the pig contracted the virus from a human," Yukol said.

Thira said that eating pork did not pose a danger.

"The virus spread from human to pigs, as in several countries. We've had no case of it spreading from pigs to humans," he said.

Since the swine flu outbreak began in April, the ministry said it has tested more than 26,000 pigs for the virus.

It has confirmed 29,741 human cases of the flu and 190 of those were fatal.

The Thai government has a one-million dollar fund set aside to combat swine flu.

Natural human Protein May Help Prevent H1N1 Pandemic Influenza

A strain of natural human proteins have been found to help ward off swine flu and other viruses including West Nile and dengue, in a discovery that could spur more effective treatments, US researchers said Thursday.

In cultured human cells, researchers lead by the Howard Hughes Medical Institute (HHMI) found that these certain proteins have powerful antiviral effects by blocking the replication of viruses.

The findings, reported Thursday in an online article from the journal Cell, "could lead to the development of more effective antiviral drugs, including prophylactic drugs that could be used to slow influenza transmission," the team said.

The influenza virus, along with the other viruses, must take over proteins in cells to sustain itself. In their study, researchers found some 120 genes that are needed by H1N1 -- commonly known as swine flu.

"But in the process of figuring that out, we found this other class of genes that actually have the opposite effect, so that if you get rid of them, influenza replicates much better," according to HHMI team leader Stephen Elledge at the Harvard Medical School.

H1N1: Swine Flu Vaccine for Children Withdrawn

Hundreds of thousands of swine flu shots for children manufactured by French drug company Sanofi Pasteur have been recalled because tests indicate the vaccine doses lost some strength, government health officials said Tuesday.

The recall is for about 800,000 pre-filled syringes intended for young children, ages 6 months to nearly 3 years. The shots were distributed across the country last month and most have already been used, according to the federal government's Centers for Disease Control and Prevention.

Doctors were notified of the voluntary recall on Tuesday. Dr. Anne Schuchat, a CDC flu expert, stressed that parents don't need to do anything or to worry. The vaccine is still safe, she said.

The issue is the vaccine's strength. Tests done before the shots were shipped showed that the vaccines were strong enough. But tests done weeks later indicated the strength had fallen slightly below required levels. Why the potency dropped isn't clear.

Children in that age group are supposed to get two doses, spaced about a month apart. Health officials don't think children need to get vaccinated again, even if they got two doses from the same lots, said Schuchat.

Swine flu vaccine has been available since early October, and since then manufacturers have released about 95 million doses for distribution in the United States.

The recalled shots were made by Sanofi Pasteur, the vaccines division of France-based Sanofi-Aventis Group. The company reported the potency findings to the government officials and did a voluntary recall. A Sanofi Pasteur representative could not immediately be reached for comment Tuesday.